Publications
Schumacher B, Hanazawa M, Lee MH, Nayak S, Volkmann K, Hofmann R, Hengartner
M, Schedl T, Gartner A. Translational repression of C. elegans p53 by GLD-1 regulates DNA
damage-induced apoptosis. Cell. 2005 Feb 11;120(3):357-68. PDF
Nayak S, Goree J, Schedl T. fog-2 and the evolution of self-fertile hermaphroditism in Caenorhabditis. PLoS Biol. 2005 Jan;3(1):e6. Epub 2004 Dec 28. PDF
Tian X, Hansen D, Schedl T, Skeath JB. Epsin potentiates Notch pathway activity in Drosophila and C. elegans. Development. 2004 Dec;131(23):5807-15. PDF
Lee MH, Schedl T. Translation repression by GLD-1 protects its mRNA targets from nonsense-mediated mRNA decay in C. elegans. Genes Dev. 2004 May 1;18(9):1047-59. Epub 2004 Apr 22. PDF
Hansen D, Hubbard EJ, Schedl T. Multi-pathway control of the proliferation versus meiotic development decision
in the Caenorhabditis elegans germline. Dev Biol. 2004 Apr 15;268(2):342-57. PDF
Wiederkehr C, Basavaraj R, Sarrauste de Menthiere C, Hermida L, Koch R, Schlecht U, Amon A, Brachat S, Breitenbach M, Briza P, Caburet S, Cherry M, Davis R, Deutschbauer A, Dickinson HG, Dumitrescu T, Fellous M, Goldman A, Grootegoed JA, Hawley R, Ishii R, Jegou B, Kaufman RJ, Klein F, Lamb N, Maro B, Nasmyth K, Nicolas A, Orr-Weaver T, Philippsen P, Pineau C, Rabitsch KP, Reinke V, Roest H, Saunders W, Schroder M, Schedl T, Siep M, Villeneuve A, Wolgemuth DJ, Yamamoto M, Zickler D, Esposito RE, Primig M. GermOnline, a cross-species community knowledgebase on germ cell differentiation. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D560-7. PDF
Hansen D, Wilson-Berry L, Dang T, Schedl T. Control of the proliferation versus meiotic development decision in the C.
elegans germline through regulation of GLD-1 protein accumulation. Development. 2004 Jan;131(1):93-104. Epub 2003 Dec 3. PDF
Primig M, Wiederkehr C, Basavaraj R, Sarrauste de Menthiere C, Hermida L, Koch R, Schlecht U, Dickinson HG, Fellous M, Grootegoed JA, Hawley RS, Jegou B, Maro B, Nicolas A, Orr-Weaver T, Schedl T, Villeneuve A, Wolgemuth DJ, Yamamoto M, Zickler D, Lamb N, Esposito RE. GermOnline, a new cross-species community annotation database on germ-line development and gametogenesis. Nat Genet. 2003 Dec;35(4):291-2. PDF
Ohmachi M, Rocheleau CE, Church D, Lambie E, Schedl T, Sundaram MV. C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are
required for MPK-1 ERK phosphorylation. Curr Biol. 2002 Mar 5;12(5):427-33. PDF
Nayak S, Santiago FE, Jin H, Lin D, Schedl T, Kipreos ET. The Caenorhabditis elegans Skp1-related gene family: diverse functions in cell
proliferation, morphogenesis, and meiosis. Curr Biol. 2002 Feb 19;12(4):277-87. PDF
Hsu V, Zobel CL, Lambie EJ, Schedl T, Kornfeld K. Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility
and the induction of vulval cell fates. Genetics. 2002 Feb;160(2):481-92. PDF
Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van
Aelst L, Hengartner MO, Ravichandran KS. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Cell. 2001 Oct 5;107(1):27-41. PDF
Lee MH, Schedl T. Identification of in vivo mRNA targets of GLD-1, a maxi-KH motif containing protein required for C. elegans germ cell development. Genes Dev. 2001 Sep 15;15(18):2408-20. PDF Supplement
Miller MA, Nguyen VQ, Lee MH, Kosinski M, Schedl T, Caprioli RM, Greenstein D. A sperm cytoskeletal protein that signals oocyte meiotic maturation and
ovulation. Science. 2001 Mar 16;291(5511):2144-7. PDF
Seydoux G, Schedl T. The germline in C. elegans: origins, proliferation, and silencing. Int Rev Cytol. 2001;203:139-85. Review. ABSTRACT
Clifford R, Lee MH, Nayak S, Ohmachi M, Giorgini F, Schedl T. FOG-2, a novel F-box containing protein, associates with the GLD-1 RNA binding protein and directs male sex determination in the C. elegans hermaphrodite germline. Development. 2000 Dec;127(24):5265-76. PDF
Kuwabara PE, Lee MH, Schedl T, Jefferis GS. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Genes Dev. 2000 Aug 1;14(15):1933-44. PDF
McCarter J, Bartlett B, Dang T, Schedl T. On the control of oocyte meiotic maturation and ovulation in Caenorhabditis elegans. Dev Biol. 1999 Jan 1;205(1):111-28. PDF
Berry LW, Westlund B, Schedl T. Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors. Development. 1997 Feb;124(4):925-36. PDF
McCarter J, Bartlett B, Dang T, Schedl T. Soma-germ cell interactions in Caenorhabditis elegans: multiple events of hermaphrodite germline development require the somatic sheath and spermathecal lineages. Dev Biol. 1997 Jan 15;181(2):121-43. PDF
Jones AR, Francis R, Schedl T. GLD-1, a cytoplasmic protein essential for oocyte differentiation, shows stage- and sex-specific expression during Caenorhabditis elegans germline development. Dev Biol. 1996 Nov 25;180(1):165-83. PDF
Crowder CM, Shebester LD, Schedl T. Behavioral effects of volatile anesthetics in Caenorhabditis elegans. Anesthesiology. 1996 Oct;85(4):901-12. ABSTRACT
Iwasaki K, McCarter J, Francis R, Schedl T. emo-1, a Caenorhabditis elegans Sec61p gamma homologue, is required for oocyte development and ovulation. J Cell Biol. 1996 Aug;134(3):699-714. PDF
Kloek AP, McCarter JP, Setterquist RA, Schedl T, Goldberg DE. Caenorhabditis globin genes: rapid intronic divergence contrasts with conservation of silent exonic sites. J Mol Evol. 1996 Aug;43(2):101-8. PDF
Jones AR, Schedl T. Mutations in gld-1, a female germ cell-specific tumor suppressor gene in Caenorhabditis elegans, affect a conserved domain also found in Src-associated protein Sam68. Genes Dev. 1995 Jun 15;9(12):1491-504. ABSTRACT
Francis R, Maine E, Schedl T. Analysis of the multiple roles of gld-1 in germline development: interactions with the sex determination cascade and the glp-1 signaling pathway. Genetics. 1995 Feb;139(2):607-30. PDF
Francis R, Barton MK, Kimble J, Schedl T. gld-1, a tumor suppressor gene required for oocyte development in Caenorhabditis elegans. Genetics. 1995 Feb;139(2):579-606. PDF
Graham PL, Schedl T, Kimble J. More mog genes that influence the switch from spermatogenesis to oogenesis in the hermaphrodite germ line of Caenorhabditis elegans. Dev Genet. 1993;14(6):471-84. PDF
Schedl T. The role of cell-cell interactions in postembryonic development of the Caenorhabditis elegans germ line. Curr Opin Genet Dev. 1991 Aug;1(2):185-90. Review. PDF
Seydoux G, Schedl T, Greenwald I. Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans. Cell. 1990 Jun 15;61(6):939-51. ABSTRACT
Schedl T, Graham PL, Barton MK, Kimble J. Analysis of the role of tra-1 in germline sex determination in the nematode Caenorhabditis elegans. Genetics. 1989 Dec;123(4):755-69. PDF
Schedl T, Kimble J. fog-2, a germ-line-specific sex determination gene required for hermaphrodite spermatogenesis in Caenorhabditis elegans. Genetics. 1988 May;119(1):43-61. PDF
Barton MK, Schedl TB, Kimble J. Gain-of-function mutations of fem-3, a sex-determination gene in Caenorhabditis elegans. Genetics. 1987 Jan;115(1):107-19. PDF