Recent Publications

Developmental origins of exceptional health and survival: a four-generation family cohort studyKeys, M. T., Netra, S., Pedersen, D. A., Larsen, P. S., Kulminski, A., Feitosa, M. F., Wojczynski, M., Province, M. & Christensen, K., Dec 2026, In: Nature communications. 17, 1, 6279.Research output: Contribution to journal › Article › peer-review

Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participantsKim, W., Hu, X., Kim, K., Chun, S., Orchard, P., Qiao, D., Ruczinski, I., Saferali, A., Aguet, F., Antonacci-Fulton, L., Balte, P. P., Bartz, T. M., Anamika, W. J., Zhou, X., Duan, J. Y., Brody, J. A., Cade, B. E., Daviglus, M. L., […]

SMURF: soft-segmentation for single-cell reconstruction and topological analysis of spatial transcriptomic dataGuo, J., Sarafinovska, S., Hagenson, R. A., Valentine, M. C., Chen, D. Y., McCoy IV, W. H., Dougherty, J. D., Mitra, R. D. & Muegge, B. D., Dec 2026, In: Nature communications. 17, 1, 7990.Research output: Contribution to journal › Article › peer-review

Publisher Correction: Whole genome sequence analysis of pulmonary function and COPD in 44,287 multi-ancestry participants (Genome Biology, (2026), 27, 1, (28), 10.1186/s13059-025-03921-y)Kim, W., Hu, X., Kim, K., Chun, S., Orchard, P., Qiao, D., Ruczinski, I., Saferali, A., Aguet, F., Antonacci-Fulton, L., Balte, P. P., Bartz, T. M., Anamika, W. J., Zhou, X., Duan, J. Y., […]

Enhancing inference of differential gene expression in metatranscriptomes from human microbial communitiesLee, E. M., McNulty, N. P., Hibberd, M. C., Cheng, J., Ahsan, K., Chang, H. W., Cohen, B. A. & Gordon, J. I., Dec 2026, In: Nature communications. 17, 1, 5490.Research output: Contribution to journal › Article › peer-review

A new chromosome-level genome assembly for western painted turtle Chrysemys picta bellii, a model for extreme physiological adaptationsChen, J., Bermingham, J. R., Minx, P., Kremitzky, M., Lin, Z. & Warren, D. E., Dec 2026, In: BMC genomics. 27, 1, 375.Research output: Contribution to journal › Article › peer-review

Lost in translation: absence of KIAA1324/ELAPOR1 protein in pathological TDP-43-affected neurons in ALS/FTDCao, M. C., Swanson, M. E. V., Basak, I., McDonald, K., Arnold, F. J., Stockford, C. M., Guo, G., Curtis, M. A., Faull, R. L. M., Hughes, S. M., Spada, A. R. L., Dragunow, M. & Scotter, E. L., Dec 2026, In: Acta […]

Sex-aware genome-wide assessment of de novo variants in autism across coding and noncoding regionsTurner, T. N., Dec 2026, In: Human genomics. 20, 1, 94.Research output: Contribution to journal › Article › peer-review

Enzyme tethering for in situ epigenomicsAhmad, K., Brahma, S., Janssens, D. H., Kind, J., Khyzha, N., Meers, M. P., Ramachandran, S., Zheng, Y. & Henikoff, S., Dec 2026, In: Nature Reviews Methods Primers. 6, 1, 42.Research output: Contribution to journal › Review article › peer-review

Expression spectrum of TE-driven transcripts in human adult tissuesMiao, B., Luo, X., Ademovic, A., Yang, Y., Wu, T. P. & Zhang, B. A., Dec 2026, In: Genome biology. 27, 1, 54.Research output: Contribution to journal › Article › peer-review

Benchmarking genome choice in functional genomics analysesHuman Pangenome Reference Consortium, Dec 2026, In: Nature communications. 17, 1, 6837.Research output: Contribution to journal › Article › peer-review

Ensilication preserves high-molecular weight native DNA for clinical long-read sequencingUndiagnosed Diseases Network, Dec 2026, In: Genome biology. 27, 1, 194.Research output: Contribution to journal › Article › peer-review

Population differences of chromosome 22q11.2 duplication structure predispose differentially to microdeletion and inversionHuman Pangenome Reference Consortium, Dec 2026, In: Nature communications. 17, 1, 3701.Research output: Contribution to journal › Article › peer-review

Antecedent enhancer activity predicts future susceptibility to seizures in miceBoros, B. D., Gachechiladze, M. A., Guo, J., Galloway, D. A., Mueller, S. M., Shabsovich, M., Yen, A., Chen, X., Cammack, A. J., Shen, T., Mitra, R. D., Dougherty, J. D. & Miller, T. M., Dec 2026, In: Nature communications. 17, 1, 300.Research output: Contribution to […]

Familial healthy aging and longevity: the role of spousesNetra, S., Galvin, A., Keys, M., Lawaetz Kristensen, K., Krabbe Pedersen, J., Thyagarajan, B., Ukraintseva, S., Wojczynski, M. K., Boomsma, D. I. & Christensen, K., Dec 2026, In: BMC Medicine. 24, 1, 355.Research output: Contribution to journal › Article › peer-review

Genetic modifiers of APOE-ε4-associated cognitive declineThe Alzheimer’s Disease Neuroimaging Initiative (ADNI), Alzheimer's Disease Genetics Consortium (ADGC) & The Alzheimer's Disease Sequencing Project (ADSP), Dec 2026, In: Nature communications. 17, 1, 2982.Research output: Contribution to journal › Article › peer-review

Oxaliplatin-induced cardiotoxicity in mice is connected to the changes in energy metabolism in the heart tissueDu, J., Sudlow, L. C., Shahverdi, K., Zhou, H., Michie, M. S., Schindler, T. H., Mitchell, J. D., Mollah, S. & Berezin, M. Y., Dec 2026, In: Cardio-Oncology. 12, 1, 39.Research output: Contribution to journal › Article › peer-review

SARM1 executes neuronal parthanatos and promotes excitotoxic cell deathWu, T., Yuan, L., Sasaki, Y., Chen, S. J., Buchser, W., Bloom, A. J., DiAntonio, A. & Milbrandt, J., Aug 19 2026, In: Neuron. 114, 16, p. 2975-2986.e5Research output: Contribution to journal › Article › peer-review

Quantifying reference alignment bias in functional genomics analysesTekkey, N., Garza, J. E., Zhang, W., Albracht, D., Tomlinson, C., Belter, E. A., Xing, X., Macias-Velasco, J. F. & Wang, T., Jul 20 2026, In: Cell Reports Methods. 6, 7, 101461.Research output: Contribution to journal › Article › peer-review

Developmental genetic determinants of the human cerebrospinal fluid–ventricular systemAllington, G., Dennis, E., Li, Q., Mcgee, S., Mehta, N. H., Mekbib, K. Y., Hatada, I., Weston, M. C., Shore, A. N., Cullen, E. R., Despenza, T., Singh, A., Miyagishima, D., Kiziltug, E., Hale, A. T., Duy, P. Q., Fan, B., Nelson-Williams, C., Moreno-de-Luca, A. & Kasper, […]